![]() The total time between sample collection and testing should not exceed 24 hours. The tube should be then inverted a few times, gently and as soon as possible, for proper mixing with the anticoagulant. The tubes must be filled to within 90% of the full collection volume. The acceptable anticoagulant is the concentration of sodium citrate 3.2%. It is recommended by the Clinical and Laboratory Standard Institutes (2017) that the blood specimens for INR/PT testing in the laboratory setting should be collected from venous blood and it is directly obtained into a tube with a light blue top. ![]() In additon, apart from adherence and treatment satisfaction some patient found to be more anxious about the PT/INR monitoring. Patient with antiphospholipid antibodies have been found to have higher error rate in INR determination. However, POC devices tend to overestimate low INR values and underestimate high INR values. Potential advantages of POC devices include improved convenience to patients, better treatment adherence, frequent measurement and fewer thromboembolic and bleeding complications. It can be performed at or near the patients with the advantage of shorter turnaround time and improved clinical outcome. POC devices are used in practitioner offices, long-term care facilities, pharmacies, or for patient self-testing or self-management. However, given the higher CCT turnaround time including collection, transportation, and processing of blood samples, Point-of-care coagulation test (POCT) also known as “bedside testing” or “near-patient testing" has been developed. ![]() Conventional coagulation testing (CCT) can be performed in the laboratory setting to measure PT/INR.
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